NOT KNOWN FACTS ABOUT METHADONE DETOX NEAR ME

[61] Like several other cardiotoxic drugs, methadone blocks the hERG K+ channel. The 2 enantiomers of methadone inhibit hERG channels with various potency. Dextromethadone, that's considerably less potent being an opioid, is more strong at blocking the hERG channel with an IC50 of ~12 μM. Levomethadone contains a lower affinity, with an IC50 of ~2